Endocrine Abstracts

Current indications for adjuvant Radioactive Iodine (RAI) in low- and intermediate-risk differentiated thyroid cancer (DTC) are controversial. At the same time, there is universal consensus for personalized DTC management according to individual patient needs, as there does not appear to be a ‘‘right’’ way to treat patients with DTC. According to the Martinique Principles 1, adjuvant RAI treatment has many goals, including: initial stagi...

Response to therapy re-stratification approach has been recently included in the 2015 ATA guidelines as a risk-adapted approach to management of thyroid cancer. Our aim was to investigate the clinical utility of response to therapy variables obtained during early follow-up in combination with BRAF, a prominent oncogene in thyroid cancer with prognostic value. This was a retrospective multicenter study of 871 patients at 11 centers in Spain with papillary thyroid cancer followe...

Obstructive sleep apnoea (OSA) is very common in severe obese patients and has been related to insulin resistance (IR) and hyperleptinemia, and these findings may have effects on food behavior and obesity complications. In order to explore this relationship and the role of sex we have studied 531 patients with morbid obesity (BMI 42.8+6.5 kg/m2). A full polysomnographic study and glucose, insulin and leptin measurements as well as air displacement plethysmography we...

The role of adjuvant external beam radiotherapy (EBRT) in differenciated thyroid cancer (DTC) is controversial. It remains unknown whether EBRT in the neck following conventional treatment might improve progression-free survival (PFS) and overall survival (OS).Objective: To assess EBRT outcomes in patients with locally advanced DTC in terms of local disease progression, PFS and OS.Material and Methods: A multicentric retrospective ...